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Dr Efevretis's avatar

Strong piece, and the flywheel section is the part that earns the whole framing.

Your own loop may undercut the node seven dismissal, though. You have eNOS switched on by shear stress, with flow driving NO driving more flow. A PDE5 inhibitor raises flow. Raised flow raises shear, which activates eNOS, which puts NO back into the pipeline. So the drain blocker does reach upstream, through the feedback loop you drew. Given your hysteresis point that recovery must overshoot rather than return, node seven looks less like the wrong node and more like the cheapest place to push the wheel.

Bitcoin Protagonist's avatar

So which company does this?

Mauricio Eugenio's avatar

Antonio excelente artículo. Un tema tan tabú y tan importante para la autoestima del hombre, que va a lo profundo de la biología, superando el status anterior limitado a recurrir a una píldora. Mil gracias por compartir tus conocimientos. Es un privilegio !

Rob de Heer's avatar

The other avenue is nervous system/adrenal dysfunction. I had a stroke and it amplified the HPA axis dysfunction I had. That put me out of business, so to speak.